Rhodaion | Protein Engineering & Design

Our Capabilities

Innovative Protein Engineering Solutions

Directed Evolution

Full service display (cell-free, phage, yeast) pipelines to drive de novo or lead candidates towards desired functions

AI/ML Design and Engineering

State-of-the-art structural prediction and sequence interpretation models to inform high-impact designs

Protein Sciences

Biochemical/biophysical characterization techniques provide insights into developability and production goals

Deep Expertise

Where Theory Meets Biology

Over a decade of experience tackling challenging problems including targeting yet-undruggable GPCRs, developing molecular biosensors, and engineering plant immunity.

✓ Led protein engineering campaign to target EBV GPCR BILF-1. Lead candidate showed minimal aggregation, high thermostability, removed liabilities, and 14 pM affinity. Patent WO2025179282
✓ Advised Engage Bio therapeutic purification strategy leading up to their acquisition by Eli Lilly
✓ Led team designing bi-stable molecular signature generators. Patent WO2021252598
✓ Developed methods to study and ultimately engineer plant immune receptors. Scientific reports 12, 501

Ready to innovate?

Partner with Rhodaion to accelerate your protein engineering pipeline.